Weekly Chest CasesCases by Disease Category

Case No : 1264 Date 2022-01-10

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  • Courtesy of Won Gi Jeon / Chonnam National University Hwasun Hospital
  • Age/Sex 66 / M
  • Chief ComplaintChief complaint: Incidentally detected pulmonary mass Past history: Endoscopic submucosal dissection (ESD) due to early gastric cancer
  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4

initial

Diagnosis With Brief Discussion

Diagnosis
Pulmonary tuberculosis
Radiologic Findings
Fig 1. High-resolution CT image shows approximately 4.5 cm mass in the left lower lobe. The mass has central ground-glass attenuation surrounded by consolidation (reversed halo sign). Nodular walls and nodules inside the halo of the reversed halo sign are noted.
Figs 2-4. The mass do not show reversed halo appearance on follow-up CT after 3 years. New solid nodules are detected in the right middle lobe and right lower lobe.
Brief Review
On surgical specimen, most of the lesions showed necrosis and TB-PCR was positive.
The reversed halo sign shown by high-resolution CT (HRCT) is defined as a focal, rounded area of ground-glass opacity surrounded by a nearly complete ring of consolidation. Cryptogenic organizing pneumonia (COP) is described as the most common cause of the reversed halo sign and this pattern can also occur in active tuberculosis. The presence of nodular walls or nodules inside the halo of the reversed halo sign is highly suggestive of granulomatous diseases, especially tuberculosis, rather than of COP. The nodular reversed halo sign should be included among the HRCT findings that are suggestive of active tuberculosis.
References
Marchiori E, Zanetti G, Irion KL, Nobre LF, Hochhegger B, Man
Keywords
Pulmonary tuberculosis,

No. of Applicants : 102

▶ Correct Answer : 7/102,  6.9%
  • - Mayo Clinic , United States AKITOSHI INOUE
  • - Chonnam National University Hwasun Hospital , Korea (South) SEONGWOO CHO
  • - Chonnam National University Hospital , Korea (South) KIM SANG GYUN
  • - Chonnam National University Hospital , Korea (South) SOMIN LEE
  • - Chonnam National University Hospital , Korea (South) SEUNG WAN KANG
  • - the first affiliatited hospital of nanjing medical univercity , China HAI XU
  • - Chonnam National University Hospital , Korea (South) EUN JU KIM
▶ Correct Answer as Differential Diagnosis : 4/102,  3.9%
  • - Osaka Red Cross Hospital , Japan YUSUKE UTSUNOMIYA
  • - , Japan CHIAKI SATO
  • - Kyoto University Hospital , Japan YASUHISA KURATA
  • - Toranomon Hospital , Japan KAORU SUMIDA
▶ Semi-Correct Answer : 1/102,  1.0%
  • - , Italy PAOLO BALDASSARI
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